Lantus And Cancer Link
In June 2009 the results of studies taken from four different regions revealed a possible link between the use of glargine and the development of cancer.
There appeared to be evidence that the risk of cancer increased with higher dosages of Lantus.
The European Medicines Agency reviewed the studies but could neither confirm or deny that a link had been found, citing that the studies were inconsistent and the data in the studies should not lead to concern in those taking the insulin.
The EMEA therefore cleared Lantus for further use until more conclusive evidence could be found to support the link.
Exceptions To Insulin Dosing And Timing
Long-acting insulins arenât tied to mealtimes. Youâll take detemir once or twice a day no matter when you eat. And youâll take glargine once a day, always at the same time. Deglutec is taken once a day, and the time of day can be flexible. But some people do have to pair a long-acting insulin with a shorter-acting type or another medication that does have to be taken at meal time.
Rapid-acting products can also be taken right after you eat, rather than 15 minutes before mealtime. You can take some of them at bedtime.
For more information about when to take insulin, read the “dosing and administration” section of the insulin product package insert that came with your insulin product, or talk with your doctor.
Drug Interactions Of Tresiba Vs Lantus
There are many classes of antidiabetic drugs, and oftentimes, people with Type 2 diabetes may need a combination of different antidiabetics to prevent hyperglycemia . Unfortunately, the combination of multiple drugs intended to lower blood sugar may decrease the glucose levels too much, resulting in hypoglycemia. Patients should be monitored closely when using Tresiba and Lantus in combination with other antidiabetic medications such as metformin and glyburide. Thiazolidinediones, such as pioglitazone, may make patients especially prone to hypoglycemia. Your dose of Tresiba or Lantus may need to be adjusted frequently.
A common class of antihypertensive drugs known as angiotensin-converting enzyme inhibitors have been shown to increase insulin sensitivity. When using these drugs to treat high blood pressure in diabetic patients also taking Tresiba or Lantus, the risk of hypoglycemia is increased. Patients should be monitored for signs of hypoglycemia if this combination is deemed necessary.
This is not intended to be a complete list of drug interactions for Tresiba and Lantus. Please consult your pharmacist or healthcare provider for a complete list.
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How To Inject Lantus Using A Solostar Pen
If your doctor wants you to use a Lantus SoloStar pen, follow these steps.
Preparing the pen
Heres how to get your Lantus SoloStar pen ready for use.
Attaching a needle to the pen
Once the pen is at room temperature and youve prepared it, youre ready to attach the needle.
Testing the pen
What Other Drugs Will Affect Lantus
Many drugs can affect your blood sugar and may also affect Lantus. Some medicines can increase or decrease the effects of insulin. Some drugs can also cause you to have fewer symptoms of hypoglycemia, making it harder to tell when your blood sugar is low. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all other medicines you use. Not all possible interactions are listed here.
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Frequently Asked Questions About Lantus
Can you take Lantus and metformin together?
Lantus can be taken with other oral diabetes medications, like metformin, if your blood sugar level needs better control. Talk to your provider about your diabetes treatment and what medications may be right for you.
What kind of insulin is Lantus ?
Lantus is a long-acting insulin that works for up to 24 hours to lower your blood sugar.
Does Lantus make you gain weight?
Weight gain is one of the most common side effects of Lantus . In clinical studies, the average weight gain was up to 1.5 lbs in adults with type 1 diabetes who took Lantus for 16 to 28 weeks.
When should you not take Lantus ?
You should not use Lantus if you are having symptoms of hypoglycemia , such as feeling shaky, nervousness, fast heartbeat, sweating or body chills, confusion, weakness or low energy, and excessive hunger. Talk to your provider or pharmacist if you are concerned about this.
What should I avoid while taking Lantus ?
Do not drive or operate heavy machinery until you know how Lantus affects you. Do not drink alcohol or use prescription or over-the-counter medications that contain alcohol.
Who Should Take Lantus
Adults with diabetes type 1 or type 2 may be prescribed Lantus.
Children with type 1 diabetes who are older than six can take Lantus.
Sometimes women with gestational diabetes may use Lantus, as well, though be sure to discuss this option thoroughly with your doctor as there may be risks to your unborn or nursing baby.
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Determining The Right Insulin Doses For You
The most challenging part of living with diabetes and requiring insulin via syringe, pen, pump, or pod is determining just how much insulin your body needs at certain times of day, and for certain types and amounts of food.
This is a never-ending process of fine-tuning, adjusting, testing, andexperimenting. Simply losing 5 pounds or gaining 5 pounds can have a significant impact on the amount of insulin you need.
Making changes in how you eat can mean you suddenly need more or less insulin. A stressful day or an entire stressful year can have a tremendous impact on your insulin needs.
Thevariables are endless.
For assistance in adjusting your insulin doses to meet your bodys current needs and prevent frequent high and low blood sugars, its imperative that you work with your medical team.
Living with diabetes is no simple task, and the medical technology and pharmaceutical drugs we require in order to stay alive are complicated and expensive. Above all else, remember that no one does diabetes perfectly. Perfect blood sugars are something we might strive for, but without a healthy pancreas and immune system, no one should expect perfection.
Dothe best you can, and never give up.
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Lantus For Type 2 Diabetes
Lantus is FDA-approved to improve blood sugar levels in adults with type 2 diabetes.
Type 2 diabetes is a chronic condition where your cells dont respond to insulin as well as they should. Insulin is a hormone that enables sugar to pass from your blood into your cells. Because your cells dont react to insulin the right way, they cant get the energy they need to work properly. In addition, sugar levels build up in your blood. If not treated, this can lead to serious complications such as nerve damage.
Some people with type 2 diabetes need to take insulin because their body stops making insulin on its own.
Note: Lantus isnt approved to treat diabetic ketoacidosis , which is a possible complication of diabetes. For more information about DKA, see the Common questions about Lantus section below.
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What Is The Most Important Information I Should Know About Lantus
You should not use this medicine if you are allergic to insulin, or if you are having an episode of hypoglycemia or diabetic ketoacidosis .
Insulin glargine is not approved for use by anyone younger than 6 years old, and some brands are for use only in adults. Do not use this medicine to treat type 2 diabetes in a child of any age.
Tell your doctor if you have ever had:
- liver or kidney disease or
- heart failure or other heart problems.
Tell your doctor if you also take pioglitazone or rosiglitazone . Taking certain oral diabetes medicines while you are using insulin may increase your risk of serious heart problems.
Tell your doctor if you are pregnant or breastfeeding.
Follow your doctor’s instructions about using insulin if you are pregnant or you become pregnant. Controlling diabetes is very important during pregnancy, and having high blood sugar may cause complications in both the mother and the baby.
How To Inject Lantus Using A Syringe And Vial
If youre going to inject Lantus using a syringe and vial, follow these steps.
Gathering supplies and preparing the vial
Before you inject Lantus, first collect your supplies and get the vial ready.
Preparing your dose
Once you have your supplies and cleaned the vial, youre ready to fill the syringe.
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What Is Lantus Used For
If you have diabetes, your doctor may prescribe Lantus.
Its a prescription drug thats used to help control blood sugar levels. Its prescribed for:
- type 1 diabetes in adults and children ages 6 years and older
- type 2 diabetes in adults
Diabetes is a condition that leads to high blood sugar. Your bodys cells use blood sugar as their primary source of energy. Your pancreas releases a hormone called insulin to help get sugar from your blood into your bodys cells.
With diabetes, your body cant effectively use the insulin thats made in your pancreas. Or your pancreas just doesnt make enough insulin.
Over time, this can cause a high level of blood sugar to stay in your blood. And having high blood sugar that goes untreated for a long time can lead to serious problems. These include heart disease and kidney disease.
Lantus is a type of insulin. It adds to or replaces the insulin your body makes naturally.
Its important to note that Lantus isnt used to treat diabetic ketoacidosis .
Do not take more Lantus than your doctor prescribes. Using more than this can lead to serious side effects.
Important Safety Information For Soliqua 100/33 100 Units/ml And 33 Mcg/ml
What is the most important information I should know about SOLIQUA 100/33?
Do not share your SOLIQUA 100/33 pen with other people, even if the needle has been changed. You may give other people a serious infection, or get a serious infection from them.
SOLIQUA 100/33 can cause serious side effects, including inflammation of the pancreas, which may be severe and lead to death.
Before using SOLIQUA 100/33, tell your doctor if you have had pancreatitis, stones in your gallbladder , or a history of alcoholism. These medical problems may make you more likely to get pancreatitis.
Stop taking SOLIQUA 100/33 and call your healthcare provider right away if you have pain in your stomach area that is severe, and will not go away. The pain may be felt in the back area. The pain may happen with or without vomiting.
Who should not use SOLIQUA 100/33?
Do not use SOLIQUA 100/33 if you:
- are having an episode of low blood sugar
- are allergic to insulin glargine, lixisenatide, or any of the ingredients in SOLIQUA 100/33. Symptoms of a severe allergic reaction with SOLIQUA 100/33 may include swelling of the face, lips, tongue, or throat, fainting or feeling dizzy, problems breathing or swallowing, very rapid heartbeat, severe rash or itching, or low blood pressure.
Before using SOLIQUA 100/33, tell your healthcare provider about all your medical conditions, including if you:
How should I use SOLIQUA 100/33?
What are the possible side effects of SOLIQUA 100/33?
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Some Side Effects Can Be Serious If You Experience These Symptoms Call Your Doctor Immediately Or Get Emergency Treatment:
- rash, hives, or itching all over the body
- wheezing
- swelling of the eyes, face, lips, tongue, or throat
- hoarseness
- swelling of ankles or feet
- shortness of breath
- vision changes
Insulin glargine products may cause other side effects. Call your doctor if you have any unusual problems while using this medication.
Reason For Pbs Listing
Insulin glargine was listed on a cost-effectiveness basis compared with isophane insulin.1 The Pharmaceutical Benefits Advisory Committee accepted that the improvement in hypoglycaemic event rates with insulin glargine, albeit in a population which cannot be defined, was cost effective at the price proposed.1,2
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What Are Insulin Pens
Insulin pens are gaining more and more popularity among patients with diabetes mellitus type 1 and type 2. These are injectable devices with inbuilt cartridges that contain insulin medication to reduce high blood sugar. The main reason for their increased popularity is the convenience and ease of usage and insulin administration.
The device is called an insulin pen because its body is in the shape of a pen. The device also consists of a fine needle to do the injections and a dial to set the needed dose of insulin preparation.
Dosing Of Insulin Glargine In The Treatment Of Type 2 Diabetes
Abstract BACKGROUND: Type 2 diabetes is a progressive disease characterized by insulin resistance and declining beta-cell function, often leading to a requirement for insulin therapy to maintain good glycemic control and prevent diabetes-associated complications. Adequate insulin dosing is crucial to the achievement of good glycemic control with minimal hypoglycemia, and dose titration immediately following insulin initiation is needed to ensure its success. Insulin may be initiated as an add-on therapy to oral treatment using a single evening basal insulin dose and titrating according to fasting blood glucose levels . OBJECTIVE: This review investigated options for, and clinical efficacy of, titration algorithms of insulin glargine in type 2 diabetes. METHODS: Articles from peer-reviewed journals were identified through searches of MEDLINE . Search terms included insulin glargine, titration, algorithm, and type 2 diabetes. Studies were assessed and included in this review if they provided information regarding the method of dose titration of insulin glargine used. RESULTS: A total of 12 studies were identified and included in this review. In the 24-week Treat-to-Target study, in which 756 patients were randomized to receive either insulin glargine or neutral protamine Hagedorn insulin, once-daily using a simple titration regimen more patienContinue reading > >
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What Is The Difference Between Basaglar And Lantus
As well as both being long-acting insulins, Lantus and Basaglar also contain the same active ingredient a type of synthetic insulin called insulin glargine. Despite this, there are differences between them. The FDA also does not consider Basaglar and Lantus to be biosimilar .
Firstly, they are made by different pharmaceutical companies. Lantus is produced by Sanofi-Aventis and Basaglar by Eli Lilly. Both medications are injected under the skin but are done so using different devices. Basaglar is injected using a pre-filled, self-injecting Basaglar KwikPen or Basaglar Tempo Pen. Lantus is injected using a pre-filled, self-injecting Lantus SoloStar pen or by using a standard syringe.
Perhaps the most significant difference between them is the price. The cost of each medication without insurance varies by retailer and quantity, but when comparing self-injecting pens containing equal amounts Basaglar is around 25% cheaper than Lantus.
Why Is This Medication Prescribed
Insulin glargine products are used to treat type 1 diabetes . Insulin glargine products are also used to treat people with type 2 diabetes who need insulin to control their diabetes. In people with type 1 diabetes, insulin glargine products must be used with another type of insulin . In people with type 2 diabetes, insulin glargine products also may be used with another type of insulin or with oral medication for diabetes. Insulin glargine is a long-acting, manmade version of human insulin. Insulin glargine products work by replacing the insulin that is normally produced by the body and by helping move sugar from the blood into other body tissues where it is used for energy. It also stops the liver from producing more sugar.
Over time, people who have diabetes and high blood sugar can develop serious or life-threatening complications, including heart disease, stroke, kidney problems, nerve damage, and eye problems. Using medication, making lifestyle changes , and regularly checking your blood sugar may help to manage your diabetes and improve your health. This therapy may also decrease your chances of having a heart attack, stroke, or other diabetes-related complications such as kidney failure, nerve damage , eye problems, including changes or loss of vision, or gum disease. Your doctor and other healthcare providers will talk to you about the best way to manage your diabetes.
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