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A Blow To The Head May Cause Diabetes Insipidus By

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Diabetes Insipidus

Commonly called blood glucose its the source of energy for our bodies cells muscles and other organs including our ains. Information about all of a sudden in the dictionary synonyms and antonyms. Drug information provided by: Micromedex.

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Examples Of Overlapping Symptoms Are:

  • Depression
  • Sexual difficulties, such as impotence and altered sex drive
  • Mood swings
  • Irregular periods/loss of normal menstrual function
  • Reduced fertility
  • Low blood pressure/dizziness
  • Diabetes insipidus

Each symptom is caused by a change in the level of a particular hormone that is produced by the pituitary gland. There are many possible causes of the above symptoms, particularly after brain injury, so a thorough assessment is required before any diagnosis can be made.

A Blow To The Head May Cause Diabetes Insipidus By : : : : : : A Blow To The Head May Cause Diabetes Insipidus By : : : : : : Triggering

Answer: interfering with the normal transmission of nerve impulses to the posterior pituitary

Explanation: A blow to the head may cause diabetes insipidus by interfering with the normal transmission of nerve impulses to the posterior pituitary. Interfering with the normal transmission of ADH to the posterior pituitary is done via the axons of the hypothalamic neurons. The disease is a rare one, characterized by the excretion of large amounts of severely diluted urine which cannot be reduced when fluid intake is reduced. It is generally related to a tumor or an insult to the pituitary gland, where the hormonal signals it gives to the kidneys break down, and the kidneys do not conserve water, but express the water as urine.

An interesting feature of the fully mature erythrocyte is that has no nucleus.


Erythrocyte, or red blood cell, is an element of the blood responsible of the transporting of oxygen and carbon dioxide, thanks to the presence of a hemoglobin molecule.

The mature red blood cell is not considered a true cell because of the absence of a nucleus, which it loses at maturity. The reason for this is to have space to contain the hemoglobin.

A red blood cell is formed from hematopoietic cells, following the erythrocyte cell line. In their immature form they are equipped with a nucleus.

The other options are not correct because:

  • The erythrocyte is not packed with organelles.
  • Its color is red

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Signs And Symptoms Of Post Head Injury Endocrine Complications

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Common post-TBI findings, such as lethargy, fatigue, and slowed mental processing time, also are associated with endocrine complications.

In extreme cases, hyponatremia can cause seizures, confusion, and coma.

Primary adrenal insufficiency may present with acute psychiatric problems, such as psychosis, depression, apathy, or a schizophrenialike syndrome.

General physical examination findings may include myxedematous, Addisonian-appearing, or slowed mentation.

Vital signs include the following:

  • Slowed pulse
  • Mesquita J, Varela A, Medina JL. Trauma and the endocrine system. Endocrinol Nutr. 2010 Dec. 57:492-9. .

  • Kaulfers AM, Backeljauw PF, Reifschneider K, Blum S, Michaud L, Weiss M, et al. Endocrine dysfunction following traumatic brain injury in children. J Pediatr. 2010 Dec. 157:894-9. .

  • Yang WH, Chen PC, Wang TC, Kuo TY, Cheng CY, Yang YH. Endocrine dysfunction following traumatic brain injury: a 5-year follow-up nationwide-based study. Sci Rep. 2016 Sep 9. 6:32987. . .

  • Tanriverdi F, Schneider HJ, Aimaretti G, Masel BE, Casanueva FF, Kelestimur F. Pituitary dysfunction after traumatic brain injury: a clinical and pathophysiological approach. Endocr Rev. 2015 Jun. 36 :305-42. . .

  • Acerini CL, Tasker RC. Neuroendocrine consequences of traumatic brain injury. J Pediatr Endocrinol Metab. 2008 Jul. 21:611-9. .

  • Hadani M, Findler G, Shaked I, et al. Unusual delayed onset of diabetes insipidus following closed head trauma. Case report. J Neurosurg. 1985 Sep. 63:456-8. .

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    Head Injury And Diabetes Insipidus

    If the kidneys are abnormal, it can affect the way they process ADH. some causes of anoxic brain injury are stroke, cardiac arrest, choking, brain tumors & asphyxia. Treatment options for the most common types of diabetes insipidus include: Central diabetes insipidus . Post-traumatic diabetes insipidus is a rare entity, usually associated with severe head trauma, often with skull fracture and cranial nerve dysfunction. Abstract: Traumatic brain injury is a significant cause of morbidity and mortality in many age groups. Nephrogenic diabetes insipidus happens when there is enough ADH, but the kidneys dont respond to it properly and cant retain the water.

    How Is Diabetes Insipidus Diagnosed

    Your doctor will do a physical exam. A checkup may not show any signs of central DI, except maybe an enlarged bladder or symptoms of dehydration.

    Theyâll ask questions about your health history, including your familyâs health. You might get a series of tests that include:

  • MRI. This test takes detailed pictures of your internal organs and soft tissues. The doctor uses it to see if thereâs a problem with your hypothalamus or pituitary gland.
  • Genetic screening. Your doctor may suggest this test if your family members have had problems with making too much urine.
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    How Are Hormonal Imbalances Assessed

    If you suspect you or a relative may be experiencing the symptoms of hypopituitarism, or any other hormonal condition, you should speak to your GP. If they feel it is appropriate, they will be able to refer you for further assessment with a specialist in the field, such as an endocrinologist. They will be able to run a variety of hormone level tests and may refer you for a scan to look for signs of damage to the hypothalamus or pituitary gland.

    The Brain And Hormones Changes

    Diabetes Insipidus

    Trauma to the brain may interfere with the normal production and regulation of the hormonal processes of the hypothalamus and pituitary glands. Th e hypothalamus and pituitary are the most vulnerable and often most affected by brain injury. Depending on the injury, problems that can occur right away include adrenal insufficiency, diabetes insipidus, and hyponatremia. Other problems may not surface until months or years later, and the most common are growth and gonadotropin hormone deficiencies leading to symptoms such as growth problems, fatigue, weight gain, low blood pressure, low libido, loss of muscle mass, and amenorrhea.

    Many studies have shown that a high percentage of patients who suffer mild, moderate, or severe TBIs may have some form of pituitary dysfunction in the first three months following the injury. While most of these patients symptoms go away over the following nine months or so, many still have pituitary hormone dysfunction by the end of a year.

    In a literature review in the February issue of Endocrine, author Alan Rogol, MD, PhD, from the division of pediatric endocrinology at the University of Virginia in Charlottesville, reported the prevalence of pituitary dysfunction following TBIs among both children and adults ranges widely from 5% to 90%. A major reason for the studies variation in ranges was the time interval between the injury and the screening for pituitary function, the review suggested.

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    What Does The Pituitary Gland Do

    The pituitary gland is a walnut-sized gland at the top of the brain stem in the lowest section of the brain. This gland produces important hormones that help regulate several bodily functions. If the pituitary gland suffers damage in the region responsible for producing human growth hormone , the victim could experience symptoms of depression, anxiety, lethargy, decreased sex drive, and excessive fatigue. About 18% of people who suffer brain injuries experience GH interruption. About 90% of the patients who do experience GH issues see them resolve naturally within about a year.

    If the pituitary gland sustains damage in the antidiuretic hormone producing region, reduced production of the ADH hormone can lead to diabetes insipidus, a form of diabetes that can entail extreme thirst and excessive urination. This can in turn lead to dehydration, and this condition occurs in about 25% of all brain injury cases. Like GH issues, ADH issues often resolve within a year on their own.

    Diabetes Insipidus Symptoms Diagnosis And Treatment Criteria

    Complications may include dehydration or seizures.. Results: Causes of Blow to the head AND Diabetes insipidus . also known as Pituitary DI or Neurogenic DI, results in a lack of ADH production. It leads to excessive diuresis and water loss, which causes very dilute urine, hypernatremia and cellular dehydration. A similar percentage of patients who have had a severe head injury develop short-term diabetes insipidus . Diabetes insipidus and diabetes mellitus which include both type 1 and type 2 diabetes although both conditions cause frequent urination and constant thirst.

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    Hormonal Imbalancesafter Brain Injury

    Brain injury may occasionally cause damage to the hypothalamus and/or pituitary gland, which are small structures at the base of the brain responsible for regulating the body’s hormones. Damage to these areas can lead to insufficient or increased release of one or more hormones, which causes disruption of the body’s ability to maintain a stable internal environment .

    If damage to the pituitary gland leads to a reduction in hormone production the resulting condition is known as hypopituitarism.

    On this page, we explain:

    Diabetes Insipidus Nclex Questions

    Ch. 16 A& P Flashcards

    The large volume of urine is diluted, mostly water. MRI of the head looking for abnormalities in or near the pituitary gland. A child with nephrogenic diabetes insipidus can lead a relatively normal life with proper medical care, especially if the medical care is started early. Basically, there are two types of diabetes insipidus in dogs: neurogenic and nephrogenic diabetes . It can be inherited or occur secondary to conditions that impair renal concentrating ability. May 31, 2019 In MS, only 2 cases of ADH deficiency have been reported without overt hypothalamic lesions. Excessive excretion of diluted urine with a low osmolarity and history of head injury are all suggestive of diabetes Insipidus .

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    Further Information And Support

    There are a number of studies into hypopituitarism after brain injury, but as yet the full extent of the problem is unknown. It seems to occur mainly after severe brain injury, however some studies have shown that damage to the pituitary gland may occasionally occur after seemingly minor head injuries. You should be particularly aware that many of the symptoms can be caused by damage elsewhere in the brain, and if this is the case treatment for pituitary dysfunction will not be effective.

    Contact the Headway helpline if you need further support or have any questions about the information on this page.

    What Causes Hypopituitarism

    Below are listed some of the causes of hypopituitarism:

    • tumours either pituitary or non-pituitary e.g. craniopharyngioma and spreading cancer
    • treatments for pituitary tumours, for example, pituitary surgery or radiotherapy
    • damage to the blood supply of the pituitary gland due to blockage or bleeding
    • injury or trauma to the head, or stroke
    • genetic errors meaning the pituitary gland cannot produce certain hormones, e.g. Kallmanns syndrome
    • damage to the pituitary gland from surgery or radiation therapy to the head, as treatment for non-pituitary tumours e.g. for the treatment of leukaemia or brain tumours
    • inflammation of the pituitary gland
    • infiltration of the pituitary gland
    • infections such as tuberculosis
    • congenital diseases or malformations of the pituitary gland.
    • Idiopathic

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    What Are The Longer

    Hypopituitarism can be transient in some cases. People with long-term hypopituitarism will need to take daily medication and will require regular checks with an endocrinologist at an outpatients clinic. They may require hospital admissions in emergency cases.

    People with hypopituitarism may have an impaired quality of life. Hypopituitarism is associated with an increased risk of heart disease and strokes as a result of the physical changes that occur in body fat, cholesterol and circulation. Healthy living, smoking cessation, a balanced diet and exercise are essential to reduce this risk.

    People with hypopituitarism also have a higher risk of developing osteoporosis or brittle bones and, therefore, have a higher risk of developing fractures from minor injuries. A diet that is rich in calcium and vitamin D along with moderate amounts of weight-bearing exercise and training are helpful in decreasing this risk.

    Appropriate pituitary hormone replacement therapy, monitoring and follow up can reduce all these risks.

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    Diabetes Insipidus in Children | Water Deprivation Test | Paediatrics

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    Diabetes Insipidus On Mri

    Diabetes insipidus is a condition in which the kidneys are unable to conserve water, often because there is insufficient antidiuretic hormone or the kidneys are unable to respond to ADH. There isnt an effective treatment for this condition. MD will monitor patient closely during these tests due to potential excess or deficient fluid loss that can lead to complications. This cycle can keep you from sleeping or even make you wet the bed. A closer look at her medication list shows a new medication, lithium, started about 8 weeks ago. A patient arrives to the ER and is unable to give you a health history due to altered mental status.

    Nclex Questions For Diabetes Insipidus

    Common causes of nephrogenic diabetes insipidus include hypercalcemia, hypokalemia, and medications like lithium . Sep 16, 2019 If you have been wondering what diabetes insipidus is, here are all your questions explained. Diabetes insipidus can lead to an imbalance of _____, like calcium, potassium, and sodium. Diabetes Awareness Survey The College of Nursing Public Health Clinical students would like you to complete this survey to assess diabetes knowledge among UND staff and faculty. A fluid or water deprivation test is a medical test which can be used to determine whether the patient has diabetes insipidus as opposed to other causes of polydipsia . Feb 26, 2019 triggering the hypersecretion of hypothalamic-inhibiting hormones A blow to the head may cause diabetes insipidus by triggering the hyposecretion of hypothalamic-inhibiting hormones interfering with the normal transmission of ADH to the posterior pituitary via the axons of hypothalamic neurons causing hypersecretion of ADH

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    What Are The Signs And Symptoms Of Hypopituitarism

    Hypopituitarism can range from being asymptomatic to collapse and coma. The signs and symptoms of hypopituitarism depend on which part of the pituitary gland is involved, to what extent and for how long. It also depends on whether the hormone deficiencies began as a child or later in adult life. Symptoms can be slow at the start and vague. It is worth understanding the normal function and effects of these hormones in order to understand the signs and symptoms of hypopituitarism. There may also be additional symptoms due to the underlying cause of the hypopituitarism, such as the effects of pressure from a tumour.

    Symptoms can include:

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