Can Type 1 Diabetes Turn Into Type 2
Diabetes is a chronic disease associated with abnormally high levels of sugar in the blood. These increasing glucose levels cause many life-threatening consequences. But a diabetic can lead a normal life through early diagnosis and effective management.
First of all, The most common types of diabetes are Two: insulin-dependent and non-insulin dependent . These Type 1 and type 2 diabetes are distinct, their etiologies are also different.
So patients with Type 1 diabetes cannot turn into Type 2. But one person can manifest both types which are really rare. Diabetes occurs due to either the pancreas not producing enough insulin or the cells of the body not responding properly to the insulin produced.
Does Type 2 Diabetes Need Insulin
People with type 2 diabetes may require insulin when their meal plan, weight loss, exercise and antidiabetic drugs do not achieve targeted blood glucose levels. Diabetes is a progressive disease and the body may require insulin injections to compensate for declining insulin production by the pancreas.
Turning Back Time: Reawakening Embryonic Genes
How was the FMD doing this? The researchers were curious too and wondered if epigenetics were responsible. They ground up some of the pancreatic tissue from the mice and used RNA sequencing to determine which genes were being expressed.
Ive covered epigenetics beforethe idea that expression of certain genes can be turned on or off, depending on what stimuli are present. Essentially, the genetic blueprint for building a pancreas is present in every single cell in the body, from the womb through adulthood, as is the blueprint for every organ and structure of your body. But this genetic blueprint only gets turned on at certain times and in certain cells, when the proper signals are present.
For example, in normal mouse development, pancreatic progenitor cells express the proteins Sox17 and Pdx1 around embryonic day 8.5. Some of these pancreatic progenitors are converted into endocrine precursor cells, which then express the protein Ngn3 from embryonic day 11.5 to 18. These Ngn3-expressing precursors ultimately give rise to all of the islet endocrine cells. These proteins are usually not expressed at all once a mouse reaches adulthood.
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What Is Worse Type 1 Or Type 2
Type 2 diabetes is a progressive condition. In type 2 diabetes, the body is unable to use insulin the right way. As a result, insulin resistance develops. So, it gets worse over time but can be reversed through proper medication and lifestyle modification. But Type 1 is totally untreatable. So type 1 is worse.
Treating High Blood Glucose
Hyperglycaemia can occur when your blood glucose levels become too high. It can happen for several reasons, such as eating too much, being unwell or not taking enough insulin.
If you develop hyperglycaemia, you may need to adjust your diet or your insulin dose to keep your glucose levels normal. Your diabetes care team can advise you about the best way to do this.
If hyperglycaemia isn’t treated, it can lead to a condition called diabetic ketoacidosis, where the body begins to break down fats for energy instead of glucose, resulting in a build-up of ketones in your blood.
Diabetic ketoacidosis is very serious and, if not addressed quickly, it can lead to unconsciousness and, eventually, death.
The signs of diabetic ketoacidosis include:
- frequently passing urine
Read more about the symptoms of diabetic ketoacidosis
Your healthcare team will educate you on how to decrease your risk of ketoacidosis by testing your own blood for ketones using blood ketone sticks if you’re unwell.
If you develop diabetic ketoacidosis, you’ll need urgent hospital treatment. You’ll be given insulin directly into a vein . You may also need other fluids given by a drip if you’re dehydrated, including salt solution and potassium.
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Can Type 2 Diabetes Become Insulin
Since Type 2 diabetes is most common amongst the type, it is possible that doctors may have diagnosis omission. A patient who is previously known as type 2 patient may be diagnosed with type 1 later. That doesnt mean that type 2 diabetes is converted to type1. Their complications are similar but onset is different. On may not convert to another overnight.
Can Anyone With Type 2 Diabetes Go Into Remission
Theres lots were still trying to understand. For example, we dont know how or whether every person with type 2 diabetes can go into remission.
Remission is more likely if you lose weight as soon as possible after your diabetes diagnosis. But, we know some people have put their diabetes into remission 25 years after being diagnosed.
We are funding further research to try and find ways for more people to go into remission. For example, the ReTUNE study is looking at how people who dont have obesity can put their diabetes into remission.
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Were We Meant To Eat Three Times A Day
Ive written before about the mismatch hypothesisthe idea that our genes have not caught up to our modern lifestyle. Our huntergatherer ancestors probably had periodic variation of food scarcity and hunting success and likely rarely ate three times a day. The ability of animals to deal with food deprivation is an adaptive response that is conserved across species. In times of scarcity, a mild atrophy of tissues and organs minimizes energy expenditure. Upon refeeding, the body can build these tissues back up to their normal volume .
This raises a few interesting questions: is expression of these embryonic genes in adulthood really abnormal? Or is it possible that we are meant to have transient expression of these embryonic genes periodically throughout our lifetime? Could our constantly fed state in most of the Western world be the true abnormal gene expression pattern? I certainly hope to see more research in this area, especially in humans.
How Is Type 1 Diabetes Diagnosed
Doctors use a blood test that measures the amount of sugar in the blood. High blood sugars show that a child has diabetes. Then, the doctor will do more blood tests to find out what type it is.
Kids with type 1 diabetes often go to a pediatric endocrinologist. This kind of doctor finds and treats problems affecting hormones, like diabetes.
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Can Type 2 Diabetes Kill You
It affects the vital organs of the body including the brain, heart, kidney. The complications of this organ lead to death. To avoid this you must go through the complications in detail.
- In heart: Diabetic patients usually unable to control their blood glucose level due to insulin resistance and some other reasons. Insulin resistance works as a risk factor for hypertension.so when both diseases come concurrently cardiovascular disease develops.
- In Brain: Glucose is the main fuel of Brain. But in type 1 diabetes there is a lack of insulin that causes a low level of insulin to enter into the cell which is very risky. It also affects the tiny blood vessels of the brain and the white matter. That results in vascular cognitive impairment.
- In the eye:Hyperglycemia is the most causative factor for developing ophthalmic complications. The main affecting site is retina & cornea. It causes diabetic retinopathy which is an inflammatory disease at the same time it is the main reason for blindness in a diabetic patient. Hyperglycemia is also responsible for epithelial dysfunctions of the corneal surface which ultimately results in loss of corneal sensation.
- In kidneys:we all know now that blood glucose plays an important role in maintaining the bodys blood pressure. But due to imbalance in glucose level, it damages blood vessels of different organs including kidneys.kidneys also help to regulate blood pressure. If diabetes is left untreated diabetic nephropathy may develop.
How Can I Get Started
So far, there is strong research evidence for two approaches that can lead to remission. Both involve losing a significant amount of weight fairly rapidly. One is to follow an intensive, low-calorie weight-loss programme of around 850 calories a day. The other approach is weight-loss or bariatric surgery, which helps you to feel full quicker and so helps you to reduce the amount you eat.
But while these are the approaches with the best quality research to put your type 2 diabetes into remission, there are other, more gradual approaches. We know that some people in remission got there by losing weight through the Mediterranean diet or a low-carb diet. Everyones different and what works for some may not for others.
You should ask your diabetes team for help with weight loss.Theyll be able to see if theres a weight management service in your area, where youll get support and advice from a dietitian. Whichever approach you consider, its important to seek support from your healthcare team. Wondering where to begin? Use our food tool to get started.
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Exercise And Weight Loss
An active lifestyle can reduce the risk of type 2 diabetes.
A healthful diet and regular exercise are the first steps to managing type 2 diabetes. Weight loss is the cornerstone of treatment for people with this condition.
A study from 2010 has shown that increased physical activity and modest weight loss can reduce the risk for type 2 diabetes by up to 58 percent.
The article in Diabetes Care stated that people with type 2 diabetes should partake in 150 minutes a week of aerobic activities, including:
- brisk walking
- bicycle riding
Breaking physical activity into five 30-minute sessions throughout the week can help a person manage this amount of exercise. This may be enough to help the body manage diabetes symptoms.
Will Type 2 Diabetes Go Away With Weight Loss
Types-2 diabetes is a progressive condition of when the body cannot control blood sugar as well as it should. It can lead to chronic high blood sugar, which is starting point for the complications to occur. There are some treatment options to cope with. How about weight loss? Does it help make diabetes go away?
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Can Type 1 Diabetes Be Treated With Pills
Is diabetes medication a drug that s pills help me? In people with type 2 diabetes, pills are only available to manage their condition, while in people with type 1 diabetes, insulin is required. Using these pills with meal planning and exercise will help you lower your blood glucose levels more effectively. This way, you can use three therapies to lower your blood glucose levels at once.
Type 1 Diabetes Treatment
People who have type 1 diabetes can live long, healthy lives. Youâll need to keep a close eye on your blood sugar levels. Your doctor will give you a range that the numbers should stay within. Adjust your insulin, food, and activities as necessary.
Everyone with type 1 diabetes needs to use insulin shots to control their blood sugar.
When your doctor talks about insulin, theyâll mention three main things:
- “Onset” is how long it takes to reach your bloodstream and begin lowering your blood sugar.
- “Peak time” is when insulin is doing the most work in terms of lowering your blood sugar.
- “Duration” is how long it keeps working after onset.
Several types of insulin are available.
- Rapid-acting starts to work in about 15 minutes. It peaks about 1 hour after you take it and continues to work for 2 to 4 hours.
- Regular or short-acting gets to work in about 30 minutes. It peaks between 2 and 3 hours and keeps working for 3 to 6 hours.
- Intermediate-acting wonât get into your bloodstream for 2 to 4 hours after your shot. It peaks from 4 to 12 hours and works for 12 to 18 hours.
- Long-acting takes several hours to get into your system and lasts about 24 hours.
Your doctor may start you out with two injections a day of two types of insulin. Later, you might need more shots.
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Annual Health Checks If You’re In Remission
Youll also want to ensure that your HbA1c levels stay below 48mmol/l or 6.5%.
Be sure to have regular health checks with your healthcare team at least once a year, including retinal screening. That way, your healthcare team can follow up on existing complications, pick up on new complications and give you support as soon as possible if your HbA1c levels go up again.
Diabetes Sick Day Rules
If you need to take insulin to control your diabetes, you should have received instructions about looking after yourself when you’re ill known as your “sick day rules”.
Contact your diabetes care team or GP for advice if you haven’t received these.
The advice you’re given will be specific to you, but some general measures that your sick day rules may include could be to:
- keep taking your insulin it’s very important not to stop treatment when you’re ill your treatment plan may state whether you need to temporarily increase your dose
- test your blood glucose level more often than usual most people are advised to check the level at least four times a day
- keep yourself well hydrated make sure you drink plenty of sugar-free drinks
- keep eating eat solid food if you feel well enough to, or liquid carbohydrates such as milk, soup and yoghurt if this is easier
- check your ketone levels if your blood glucose level is high
Seek advice from your diabetes care team or GP if your blood glucose or ketone level remains high after taking insulin, if:
- you’re not sure whether to make any changes to your treatment
- you develop symptoms of diabetic ketoacidosis
- you have any other concerns
Read more about sick day rules
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Diabetes And Your Child
For a parent whose child is diagnosed with a life-long condition, the job of parenting becomes even tougher.
Although being diagnosed with type 1 diabetes will involve coming to terms with the diagnosis, getting used to treatment and making changes to everyday life, your child can still lead a normal and healthy life.
The Diabetes UK website has information and advice about your child and diabetes.
Whats The Difference Between Signs Vs Symptoms Of Type 1 Diabetes
Type 1 diabetes symptoms are experienced by a person with diabetes, but signs of type 1 diabetes can also be noted by friends and family even if the person who is having the symptoms may not notice them or may be unable to communicate because they are in the throes of diabetic ketoacidosis. Common signs of T1D to watch out for include:
- Weight loss, despite eating more
- Changes to menstruation
- Rapid heart rate
- Reduced blood pressure
- Low body temperature
- Acting or seeming drunk while sober, which is a sign of diabetic ketoacidosis
- Breath that is fruity or smells like nail polish remover which is another sign of ketosis
- Chronic skin infections
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What Are The Signs & Symptoms Of Type 1 Diabetes
Type 1 diabetes can come on over time or suddenly. Sometimes, kids dont have diabetes symptoms yet and the condition is discovered when blood or urine tests are done for another reason. Kids who show symptoms may:
- need to pee a lot
- start to wet the bed after having been dry at night
- be thirstier and drink more than usual
- feel tired often
- lose weight
What Is A Fasting Mimicking Diet Anyway
We know that water-only fasting provides many health benefits, including reduced blood glucose, regeneration of the immune system, and cellular maintenance . But prolonged fasting is difficult for most people and can cause adverse effects on physical and mental health due to its extreme nature. Researchers have therefore been attempting to design diets that mimic the physiological benefits of prolonged fasting without the burden of complete food restriction.
Fasting mimicking diet may reverse type 1 diabetes
This type of diet is called a fasting mimicking diet . It is a very-low-calorie, low-protein, high-fat diet that causes changes in glucose, ketone bodies, and specific growth factors similar to those seen during prolonged water-only fasting. The FMD is characterized by cycles of caloric restriction and refeeding. For example, in mouse models of FMD, researchers restrict the amount of food the mouse has access to for four days, followed by three days of unrestricted feeding every week. In humans, one FMD cycle consists of five days of restriction, and eating resumes as usual for the rest of the month. This is typically repeated for three months .
Soon, well jump into the results of the study to look at the intriguing effects of an FMD. But first, lets briefly review what happens to the body in type 1 diabetes.
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Common Questions About Type 2 Diabetes:
- Can type 2 diabetes go away?
- Will I need to take insulin?
- Do I have to take it forever?
How do you treat type 2 diabetes?
When you have type 2 diabetes, you first need to eat a healthy diet, stay physically active and lose any extra weight. If these lifestyle changes cannot control your blood sugar, you also may need to take pills and other injected medication, including insulin.
Eating a healthy diet, being physically active, and losing any extra weight is the first line of therapy. Diet and exercise is the foundation of all diabetes management because it makes your bodys cells respond better to insulin and lowers blood sugar levels.
If you cannot normalize or control the blood sugars with diet, weight loss and exercise, the next treatment phase is taking medicine either orally or by injection.
Diabetes pills work in different ways some lower insulin resistance, others slow the digestion of food or increase insulin levels in the blood stream. The non-insulin injected medications for type 2 diabetes have a complicated action but basically lower blood glucose after eating. Insulin therapy simply increases insulin in the circulation.
Many people with type 2 diabetes have elevated blood fats and blood pressure, so you may be given medications for these problems as well.
Can type 2 diabetes go away? And if my blood sugar becomes normal, do I still have diabetes?
Will I need to take insulin if I have type 2 diabetes?