What Is Diabetes And Who Should Care
Diabetes is a problem of energy processing. At the root of the problem is insulin, a hormone made in the pancreas, an organ in the abdomen.
Insulin helps the body regulate the amount of glucose in the body. This is how the body knows how much glucose is needed for energy now, and how much needs to be saved for later.
There are four main types of diabetes:
Type 1 diabetes
Other rare types of diabetes
All have a different problem with insulin, but the end result is the same: harmful, high blood glucose levels in the blood.
Both Type 1 and Type 2 diabetes are chronic conditions. This means that people with diabetes need to live with the condition and usually take medications for the rest of their lives. Diabetes can also cause a myriad of other health problems, so the emotional, physical, and financial costs of living with diabetes really add up.
Type 1 diabetes affects fewer than 5% of people with diabetes. It is usually diagnosed in childhood or the teenage years, and there is nothing you can do to prevent it.
Type 2 diabetes is much more common, affecting about 95% of all people with diabetes. The pancreas often produces enough insulin, but the body doesnt recognize it. Many people with T2D have a family history of diabetes, but with healthy lifestyle changes, the condition can be prevented or slowed down.
How About Pancreas Transplantation
Getting a transplanted pancreas is a possibility for some people with type 1 diabetes. It’s usually done in those who also have end-stage kidney disease.
A pancreatic transplant would help restore blood sugar control. Like anyone else who gets a transplant, the patient would need to take medicine for the rest of their life to help their body accept their new pancreas.
Exercise And Weight Loss
An active lifestyle can reduce the risk of type 2 diabetes.
A healthful diet and regular exercise are the first steps to managing type 2 diabetes. Weight loss is the cornerstone of treatment for people with this condition.
A study from 2010 has shown that increased physical activity and modest weight loss can reduce the risk for type 2 diabetes by up to 58 percent.
The article in Diabetes Care stated that people with type 2 diabetes should partake in 150 minutes a week of aerobic activities, including:
- brisk walking
- bicycle riding
Breaking physical activity into five 30-minute sessions throughout the week can help a person manage this amount of exercise. This may be enough to help the body manage diabetes symptoms.
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The Revolutionary Stem Therapyin Type 1 Diabetes
2015figures recorded by CDC- Centerfor Disease Control and Prevention stated that at least 30 million US citizenshad been diagnosed with diabetes that year, while 415 million people are saidto suffer from the disease across the globe. Those that required daily insulin treatmentwere about 5 percent. This number continues to rise.
The standard treatmenttoday for type1 diabetesinvolves the monitoring of glucose levels and the injection of insulin to maintainhealthy blood sugar levels. Despite these measures, patients are still facedwith complications such as kidney and nerve problems. Uncontrolled diabetes type 1 can alsobe potentially fatal. When having Type 1 Diabetes, the pancreas make little orno insulin. Insulin is responsible forallowing blood sugar to get into your cells for energy. Without which will cause bloodsugar to build up in the bloodstream.
A study done by theUniversity of Copenhagen shows that new pancreatic cells used to replace islets can benefit diabetes type 1 sufferers.The study shows how the production of insulin could be increased. Should stem therapy continue tobear fruit, it will offer realistic solutions for type 1 diabetics. Pancreas transplant is asolution that can solve the problem, but it does not come with a 100 percentsuccess rate and normally requires medication that suppresses immunity.
Is There A Natural Therapy That Can Cure Diabetes
No. Natural therapies such as deep abdominal breathing, progressive muscle relaxation, guided imagery, and biofeedback can help relieve stress. And emotional stress affects your blood sugar levels. So learning to relax is important in managing your diabetes.
Supplements don’t cure diabetes, either. Some natural supplements may interact dangerously with your diabetes medication. Others have been shown to help improve your diabetes, but always check with your doctor before taking any supplement.
Be skeptical about claims of a diabetes cure. A genuine cure will have been tested repeatedly in clinical trials with clear success.
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Could The Newly Devised Therapy Cure Diabetes Type 1
Althoughthere have been advances in the past to try and differentiate insulin-producinghormones from embryonic stemcells, functionaland mature B cells generation has proven elusive. As a result, scientists haveresearched and discovered the fate of immature hormones. According to the latest scientific news on type 1 diabetes, the cells are mobile and theenvironment they are exposed to influences them. It means pancreatic islet cells can be manufacturedfrom stem cells toreverse the disease.
Becauseimmunity is to blame for the destruction of beta islet, researchers are now looking at optionsin keeping the immune system stable, to cure type 1 diabetes. Studies show that there arereplacement therapies that can be used to generate beta cells from stem cells.
Managing Type 1 Diabetes
Type 1 diabetes is an autoimmune disease that often develops during childhood. It occurs when the body mistakenly attacks the beta cells of the pancreas, removing their ability to produce the insulin that the body needs to use blood sugars correctly.
Receiving a diagnosis of type 1 diabetes can be daunting, yet many people manage the condition well, keeping symptoms and severe complications at bay.
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Type 1 Diabetes Treatment Technologies
Technologiessuch as sensors that give accounts of the rise and fluctuation of blood glucoselevels and pumps, used to deliver insulin automatically, are intended to boostthe regulation of blood sugars and prevent complications. Today, there are alsoartificial pancreas systems used to deliver the right dose at given times ofthe day. Although these new models are ethical, effective, and convenient, anyone with type 1 diabetes cannotrely on them for a cure.Could stem therapy be the cure type1 diabetics need?
How Close Are We To A Cure For Type 2 Diabetes
Type 2 diabetes is one of the worlds greatest health problems. It affects about 400 million people globally. If its uncontrolled, it can lead to dangerous complications like kidney failure, blindness, heart attack, and stroke. But while there are over 30 different drugs on the market to help manage this disease and prevent these problems, none provide an actual cure.
One reason is that until recently, we didnt quite understand the full scope of the problem. Two decades ago, if you asked a diabetes specialist to explain the cause of type 2 diabetes, they would say insulin resistance. Insulin is a hormone made by the pancreas that helps the glucose in your blood enter cells in your muscle, fat, and liver, where its used for energy. But when you have insulin resistance, these muscle, fat, and liver cells dont respond well to it. As a result, your pancreas has to make more and more insulin to compensate. Over time, this can lead to type 2 diabetes.
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Is There A Cure For Type 2 Diabetes
Theres no cure yet, but our scientists are working on a ground-breaking weight management study, to help people put their type 2 diabetes into remission.
Remission is when blood glucose levels are in a normal range again. This doesnt mean diabetes has gone for good. Its still really important for people in remission to get regular healthcare checks. But being in remission can be life changing.
Our ground-breaking study is called DiRECT, short for Diabetes Remission Clinical Trial, and it could completely change the way type 2 diabetes is treated in the future.
How To Get Free Prescriptions For Diabetes Medicine
You’re entitled to free prescriptions for your diabetes medicine.
To claim your free prescriptions, you’ll need to apply for an exemption certificate. This is known as a PF57 form. To do this:
- fill in a form at your GP surgery
- you should get the certificate in the post about a week later it’ll last for 5 years
- take it to your pharmacy with your prescriptions
Save your receipts if you have to pay for diabetes medicine before you receive your exemption certificate. You can claim the money back if you include the receipts along with your completed PF57 form.
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What Is Needed To Cure Type 1 Diabetes
Type 1 diabetes happens when the body doesnt make insulin at all, or very little of it. The bodys immune system destroys the cells in the pancreas that are responsible for making insulin. A cure for T1D needs to do two things:
Stop the immune system from destroying the pancreas cells that make insulin
Replace the cells that have been lost
So far, there is no treatment that does this. The best treatments we have are medications and devices that do the pancreas job of making insulin. But that job is easier said than done. Insulin works in a very fine balance with other hormones to respond to the foods you eat. The right amount has to be released at the right time.
This is why it is so important if you have Type 1 diabetes to check blood sugars often, know what you eat, and take the right amount of insulin medication. You need to make sure you get enough insulin, but too much can be deadly: Low blood sugar is a true medical emergency.
Managing your blood sugar can be tough in diabetes treatment plans because youre trying to copy a complicated system that the body uses to keep blood glucose in a very tight range at all times. Many things are happening in the background that people without diabetes take for granted.
Pancreas transplants are major and very risky surgeries. Like all major surgeries, there are risks of severe complications such as infections, bleeding, and even death.
About 8% of patients who get a pancreas transplant will get diabetes again.
Enhancing The Survivalof Beta Cells
The insulin-producing cells live in clusters knownas islets containing different types of cells that produce hormones. Beta cells makeinsulin. Stem cell research for diabetes shows that islet transplantation canbe a successful alternative to insulin injections. This treatment does not require invasive surgeryand would be able to trigger better glucose control and reduces complicationscommon with type 1diabetes.
Although there ispromise with the stemtherapy as a formof treatment, derived stem islets tend to have a low survival rate. This is dueto the lack of adequate nutrients and oxygen. Researchers are now studying howthe shortage of nutrients and oxygen occurs and how the functioning of stemcell-derived beta cellscan be improved. Research has shown that beta cells can be trained to survive theseshortages before and after the process. Should this new approach be successful,there will be improved clinical options for the replacement of destroyed beta cells.
The current treatments for autoimmuneconditions such as diabetestype 1 neutralize the immune cells known to attack the healthy tissue.The problem is most of these therapies end up destroying cells that are functioning well in the body,leaving you exposed to other ailments. This is mostly a result of immunereactions against foreign cells.
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Automated Treatment With An Artificial Pancreas
For people that have already lost their insulin-producing cells, a shorter-term solution could be the artificial pancreas a fully automated system that can measure glucose levels and inject the right amount of insulin into the bloodstream, just like a healthy pancreas would.
Type 1 diabetes is very different from your standard disease. Insulin requirements vary greatly from one day to another and there is no way patients can know what they need, saidRoman Hovorka, Professor at the University of Cambridge.
His research group is working on the development of an algorithm that can accurately predict insulin requirements for a specific patient in real-time, which can be used to control insulin delivery via an insulin pump.
Replacing humans with computers could help patients better control their sugar levels and suffer fewer complications in the long term. However, in order to fully automate insulin therapy, there are several challenges yet to be addressed. First of all, faster forms of insulin are needed to react quickly enough to changes in sugar blood. In addition, current algorithms need to significantly improve to be able to make accurate predictions.
What Exactly Is Glucofort
Glucofort is founded by Andrew Freeman, 50, whose story that caused a revolution within the diabetes neighborhood. He is practicing psychologist who, when notified of his type 2 diabetes diagnosis, could not believe what he heard, particularly knowing how careful he had actually been with his health.
He decided to use his experience & connections to develop a practical service that is safe yet efficient. After numerous hours of research study, Andrew declares to have actually discovered the diabetes-reversing secret lost in eastern Asia.
Glucoforts blood sugar support, enabled by what Freeman discovered, works by increasing insulin production while reducing its resistance into your cells. It likewise supports healthy glucose metabolism. The formula in this natural supplement just enables needed glucose to be kept in the body and burns the rest by transforming it into energy.
In addition, Glucofort supports cardiovascular health and helps reduce the chances of heart-related diseases on top of being used to help treat type-2 diabetes. Plus, no significant way of life modifications are required! No more stressing about strict dieting strategies or extensive exercises to take advantage of the advantages.
You can likewise expect it to assist in weight-loss because of the components balancing blood sugar levels, which is the initial step to control weight.
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Is There A Conspiracy Preventing A Diabetes Cure
For as long as there has been research to cure diabetes, there have been people who believe that a cure will never happen because treating this disease is simply far too profitable. Those who believe in this so-called conspiracy theory are convinced that pharma companies have a vested interest in keeping diabetes around as long as possible because peddling their treatments is far bigger business than a cure could ever be.
We all know that diabetes is a multi-billion dollar industry, including sales of insulin, oral agents and injectibles like Victoza, and medical devices such as insulin pumps, glucose monitors and their pricey test strips, and new continuous glucose monitors. Type 2 diabetes is increasing exponentially, but even type 1 diabetes is growing at a dramatic rate, which means more and more consumers.
The latest flare-up over a possible conspiracy occurred in August, when a news article about controversial researcher Dr. Denise Faustman circulated around the diabetes community. In the article, Faustman says that when she approached pharmaceutical companies for funding, she was told there wasnt enough money to be made in a cure that used an inexpensive, generically available vaccine.
But is that even true?
Whos to say?
We decided it would be fascinating to tap some prominent experts in the diabetes community to get their perspective on the D-conspiracy theory.
A Terrible Terrible Disease
Dr. Melton had never thought much about diabetes until 1991 when his 6-month-old baby boy, Sam, began shaking, vomiting and panting.
He was so sick, and the pediatrician didnt know what it was, Dr. Melton said. He and his wife Gail OKeefe rushed their baby to Boston Childrens Hospital. Sams urine was brimming with sugar a sign of diabetes.
The disease, which occurs when the bodys immune system destroys the insulin-secreting islet cells of the pancreas, often starts around age 13 or 14. Unlike the more common and milder Type 2 diabetes, Type 1 is quickly lethal unless patients get injections of insulin. No one spontaneously gets better.
Its a terrible, terrible disease, said Dr. Butler at U.C.L.A.
Patients are at risk of going blind diabetes is the leading cause of blindness in this country. It is also the leading cause of kidney failure. People with Type 1 diabetes are at risk of having their legs amputated and of death in the night because their blood sugar plummets during sleep. Diabetes greatly increases their likelihood of having a heart attack or stroke. It weakens the immune system one of Dr. Butlers fully vaccinated diabetes patients recently died from Covid-19.
Added to the burden of the disease is the high cost of insulin, whose price has risen each year.
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Stop The Immune Attack
In type 1 diabetes, the immune system is unable to tell the difference between harmful germs and the body’s cells and tissues, so the immune system attacks the bodys own insulin producing beta cells.
One way to cure diabetes could be to persuade a badly behaved immune system to accept the beta cells as part of the body.
Some of the immune system culprits attacking the beta cells are T cells. T cells develop in the thymus gland and, from a naïve or undifferentiated state, they are gradually educated to become helpers, warriors, or regulators.
In type 1 diabetes, the helper and warrior T cells work together to kill the beta cells, while the regulators appear unable to stop this from happening.
A/Prof Grey’s team worked up a vaccine, called BCMA-Fc, that re-dressed this imbalance. When given to mice with a disease similar to type 1 diabetes, the vaccine prevented diabetes by increasing the number of regulator T cells and reducing the number of warriors.
This work shows the potential of stopping the immune attack as a way to prevent type 1 diabetes. It has supported the testing of a related compound, called rituximab, in people with promising results. In a USA trial, people kept the ability to produce their own insulin, after diabetes had started, for up to 18 months. Further study will test whether taking this drug repeatedly will continue to maintain insulin production.