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Does Insulin Have To Be Refrigerated

Does Novolog Insulin Need To Be Refrigerated

Storing your insulin pen

If this question focuses on whether Novolog insulin needs to be refrigerated as soon as you get it, then the answer would be no. Insulin does not need to be immediately placed in the fridge to ensure its effectiveness.

Most insulin manufacturers say that a vial of insulin including Novolog can be kept at room temperature for up to 28 days. However, for unopened insulin to maintain effectiveness until the expiration date, it should be refrigerated.

The room temperature for Novolog in-use can be kept at ranges between 59 degrees and 86 degrees Fahrenheit. The temperature for not-in-use Novolog insulin can range between 36 degrees and 46 degrees Fahrenheit.

This temperature range can vary as it may depend on the place you live in and other environmental factors.

If the temperature gets colder or warmer than these recommended temperatures for Novolog insulin, then it means that the insulin will either freeze or will end up breaking down when its too warm.

Breaking down in this respect means that the insulin will allow the growth of bacteria, which will make the insulin less effective or potent.

So, if you live in a place that has a room temperature above or below the recommended temperature, its advisable to refrigerate your Novolog insulin to keep it at the recommended temperature.

Note When Novolog insulin is kept at room temperature, its important to make sure its kept away from sunlight, heat, and any other direct heat sources.

Ot: Insulin Need Not Be Refrigerated

I’m a pediatrician with a number of diabetic patients and this question comes up every time families are getting ready for travel.


It is advised that for long term storage, insulin be kept refrigerated. So, when you are at home, it is perfectly reasonable to keep your stock in the refrigerator. But it is good at room temperature for up to a month. In fact, most forms of insulin are LESS EFFECTIVE if they are too cold.

Excessive high temperatures will damage insulin. But for most travelers, keeping insulin at room temperature is perfectly fine.


Pantient & Family Education / NYU Medical Center, Information About Insulin

“Insulin vials in use can be stored at cool temperatures under 86 F. However, it is not recommended that opened insulin vials, whether refrigerated or kept in room temperature, be used for more than 28 days.”

American Diabetes Association: Traveling With Diabetes

“When you travel with insulin, give some thought to where you’ll be storing your supplies. Insulin does not need to be refrigerated. But insulin stored in very hot or very cold temperatures may lose strength.”

Joslin Diabetes Center: Helpful Hints on The Use of Insulin

If you are uncertain, contact your physician and ask him or her.

There, I’ll get off my soapbox now.

A lot of people will be pleased with this info.

You’re a real bummer, pal.

Looking At The Alternatives

People, however, dont want to throw their insulin away, especially as the price of insulin has skyrocketed in recent years.

That puts more pressure on patients who need the hormone to make sure its stored safely and none of it is wasted.

There are some solutions in the works.

The Cleveland-based Thermalin, Inc., for instance, has been working on an insulin that never needs to be refrigerated and can sustain temperatures up to 130°F, the Cleveland Plain Dealer reported.

In the meantime, people who use liquid insulin that needs to be refrigerated, should keep a closer eye on their refrigerator temperature.

Many people with diabetes are unwittingly storing their insulin wrong because of fluctuating temperatures in domestic refrigerators, Dr. Katarina Braune, a research fellow at Charite Universitaetsmedizin Berlin in Germany, and the lead author of the recent study, said. When storing your insulin in the fridge at home, always use a thermometer to check the temperature. Long-term storage conditions of insulin are known to have an impact on its blood-glucose lowering effect.

Susan Weiner, a registered dietitian-nutritionist and certified diabetes educator, agrees.

Getting a temperature sensor is a really fantastic idea, she told Healthline.

And not everywhere in the refrigerator is created equal.

That said, even if your insulin does occasionally fall out of the manufacturers recommended range, that doesnt mean you have to get rid of it immediately.

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How Long Does Cat Insulin Last

A bottle of cat insulin should last for 6 to 8 weeks or even longer if you follow the following instructions:

  • Insulin should always be kept refrigerated.
  • Do not clean the syringe with water before taking insulin out of the bottle.
  • Do not shake it before taking insulin out with syringe.
  • Dont touch the rubber stopper with your fingers.

Insulin is a sterile suspension. So it needs special care to stay effective. If you want to keep the insulin to its 100% effective, you need to take a couple of measures. If you are not careful, then you might end up damaging the insulin.

For example, you need to be careful not to touch the rubber stopper with your finger, and you cant clean the syringes with water in any way.

When you want to use the insulin for your cat, you need to mix it correctly. When mixing the insulin, do not shake the insulin. It is very sensitive, and it will get damaged if you shake it too harshly. And if you notice that its changing its color, then you need a new bottle. So if you can maintain the regulations, then a bottle should last for 6 to 8 weeks and more.

Why Does Insulin Have To Be Refrigerated

Does Insulin Go Bad If Not Refrigerated? Guide on Insulin Storage ...

Insulin is a temperature-sensitive medication used for the treatment of both type 1 and type 2 diabetes. This synthetic human-like hormone allows diabetics to lower their blood glucose levels. It is very sensitive to extreme temperatures and temperature changes.Insulin that has frozen or gotten too warm is good for trash. Here’s a little reminder of adequately storing your insulin and keep its potency to the maximum.

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Why Does This Guideline Still Exist For Pen Cartridges

Novos medical information clarifies: We wanted to allow refrigerator storage for insulin pens in-use again. However, pen cartridges were not cleared by the authorities, because many of the new pens have built-in digital functions, which can be affected by condensation in refrigerators.

When asked what to do, if no other cooling option than a fridge is available, they also had a solution at hand: a zip lock bag to protect from moisture.

Did I Cover All You Wanted To Know About Weather Cat Insulin Needed To Be Refrigerated Or Not

Storing your cats insulin in the refrigerator is very important. If you dont keep it in the fridge, it will lose its effectiveness, and it will do nothing to your cats diabetes.

If you do not inject insulin, then your cat will face high blood sugar. So its always best to inject the insulin timely. But if your insulin loses its effectiveness, then it will do nothing to your cat, and your cat will face high blood sugar levels.

So we hope that you got the answer to the question- Does cat insulin need to be refrigerated? And know exactly when you need to inject the insulin and how to inject it in the cat.

Moreover, you must understand how to store your insulin. However, if you notice or face any complications, then contact a professional vet immediately.

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Accessories To Protect The Temperature Of Your Insulin

If you dont want to buy something new, you can always keep an ice-pack with you when youre out and about in the summer. Keep the ice-pack in the same bag as your diabetes kit containing your insulin. It doesnt have to be complicated or expensive, but it needs to be a priority for anyone taking insulin.

There Are Some Very Simple Products To Help Protect Your Insulin

Fridge temperature may make insulin less effective for diabetic patients

The Frio Pack is one of the simplest and most affordable storage products to keep your insulin cool in hot environments. The basic model costs $22.99, and requires zero refrigeration. Instead, its a unique technology that is activated by immersing the pack in water for a few minutes. Give it a quick towel-dry, put your insulin inside, and off you go. You can reactivate it as often as you need to.

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Protecting Your Insulin Vials

Getting insulin requires seeing a doctor and getting a prescription. And then there’s the actual cost, which has increased rapidly over the past few years.

Depending on your insurance coverage, one vial can cost as much as $300. Many people with diabetes require more than one shot a day, which means more than one vial a month.

Given the high cost, you may want to consider investing in an insulin vial protector. These silicone covers wrap around glass insulin vials and protect them from shattering if you accidentally drop them. They cost between $6 and $9 apiece.

We All Know That Unopened Insulin Must Be Kept In The Refrigerator But Once In Use It Cant Go Back The Story Of Origin And Quiet Disappearance Of A Confusing Guideline

All manufacturers explicitly recommend to Not refrigerate insulin pens in use. Why? It was kept in the fridge before, how can it hurt the insulin now that its open? Lets imagine it was a hot summer day. Is it worse to put my insulin pen in the fridge or expose it to heat? What is even more confusing, the guidelines start changing now! Lets take a step back and look at the basics:

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Insulin Has Two Expiration Dates

Its true, insulin has two different expiration dates you should keep track of. The one printed on the product by the manufacturer. And the one arriving about a month after you first opened your insulin or took it out of the fridge.

In both cases, past the expiration date, the stability and potency of your insulin are not guaranteed anymore. Do not take any chances. Dispose of it immediately and open a new one.

Note: insulins stability once opened or out of the fridge slightly varies depending on the brand youre using. Some insulins are good for only 28 days once opened , while others can last up to 31 days , 42 days , or even 56 days .

Insulin expiration dates slightly vary depending on the brand

Insulin May Not Need To Be Refrigerated After All Study Shows

Does Cat Insulin Need to be Refrigerated?

By Elizabeth Morey

Until recently, it was believed that insulin needed to be stored in a cool place and was best kept in a refrigerator in order to ensure that it would be good up until its expiration date. However, recent research has found that not only does insulin not need to be refrigerated, but it can also survive undamaged in temperatures much hotter than one would likely expect.

The study, conducted by Doctors Without Borders and the University of Geneva and published in the PLOS One medical journal, involved recording temperatures at the Dagahaley refugee camp in northern Kenya and reproducing those temperatures over four weeks at their laboratory. Four weeks is the time it usually takes someone with diabetes to finish a vial of insulin.

The study results showed that insulin did not lose its efficacy after being opened and then stored for four weeks in temperatures ranging from 77 to 98.6 degrees Fahrenheit .

In a news release, the team revealed that the stability of insulin stored under these conditions is the same as that of cold-stored insulin, with no impact on efficacy. Only one percent of potency was lost over the test period, the same as in a control batch of insulin that was kept in cold storage.

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How Long Can Cat Insulin Be Unrefrigerated

You can keep insulin unrefrigerated for a day or two, only if it isnt exposed to direct sunlight. Insulin is a hormone, so if it is exposed to direct sunlight or high temperature, the insulin element will break down, and it will lose effectiveness. So it would be best if you kept the insulin inside refrigerated.

Insulin is a hormone that we use to control our blood sugar levels. Also, insulin is being used to control cats blood sugar levels too.

You can also use human Lantus or Glargine insulin on cats. Cats insulin is made with vetsulin and protamine zinc specifically or PZI.

If your cat has diabetes, then it needs consistent medication and administration. You need to change the cats diet, measure blood sugar level regularly, and give it insulin shots whenever required.

Standard Temperature For Refrigerating Insulin

As mentioned, insulin can be kept at room temperature for a maximum approximation of 28 to 30 days. The standard recommendation from all insulin manufacturers says a vial of insulin in use can be kept at room temperature for 28 days.

Room temperature for insulin in use specifies a temperature range between 59 degrees and 86 degrees Fahrenheit. The temperature for insulin not in use should be kept at a temperature between 36 degrees and 46 degrees Fahrenheit.

If the temperature gets colder or warmer than that, itll either freeze or start to break down as a result of being too warm. The term break down again refers to when the bacteria starts growing, making the insulin ineffective or lose its strength.

If you live in a warmer climate, its safer for you to refrigerate your insulin when the temperature goes above about 80 degrees Fahrenheit, even if the maximum 28 days are not over.

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Insulin Is A Protein And It Can Wery Easily Spoil Under The Wrong Temperature Conditions

Insulin prefers to be kept between 36° to 46°F. When an insulin vial or pen is opened, it will retain its potency to help you manage your blood sugar for up to 28 days before it starts to break down. Using insulin that has broken down due to time or temperature results in higher blood sugars because your usual dose doesnt contain its usual strength and efficacy.

Check Insulin Before Using It

Storing Insulin and Perishable drugs in SHTF

Because insulin is temperature-sensitive, it can become damaged as it is being transported or delivered. There are things you can do to make sure your insulin was handled properly before you got it.

If you pick up your insulin at a pharmacy, it shouldn’t be sitting out. The pharmacist should have to go to a fridge to get it for you.

Mail order insulin should arrive sealed in a temperature-controlled box. Insulin can become spoiled if it is delivered on a very cold or hot day and left outside for a while. You may want to talk to your mail carrier about this. Use either an app or text messaging to track your deliveries.

If you suspect your insulin was damaged during delivery, don’t use it. Always inspect your insulin before you inject it. If you see white clumps, particles, or crystals, or if your insulin has become cloudy or is a different color, don’t use it.

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Does Insulin Need To Be Kept Cool

Yes, keeping insulin cool is very important. But it depends on the environmental temperature. Unused bottles and insulin pens need to be kept in the refrigerator between 36°F and 46°F. Keep an eye on the expiration date. insulin pens and vials that you are currently using can be stored at room temperature between 56°F and 80°F.

If you are traveling in cold temperatures make sure to keep your insulin warmer than prescribed. It should not freeze or it will be damaged. When traveling in warmer temperatures keep your insulin cooler. You might want to use an insulin cooler or travel case. I traveled in very hot temperatures in Australia and Sri Lanka. I used the Frio cooling bags to store my vials safe and cool while flying on an airplane. When I traveled in the Australian outback I used the 4ALLFAMILY Insulin Cooler.

Insulin May Not Need Refrigeration Freeing Up Its Use In Poorer Nations

THURSDAY, Feb. 4, 2021 — Researchers report that insulin can be stored at less-cold temperatures than previously known, potentially simplifying diabetes care for people in warmer regions that have fewer resources.

Researchers from Doctors Without Borders and the University of Geneva tested insulin storage in real conditions ranging from 77 to 98.6 degrees Fahrenheit for four weeks — the time it typically takes to use a vial.

They found that the stability of insulin stored under these conditions was the same as that of cold-stored insulin, with no impact on its effectiveness.

“These results can serve as a basis for changing diabetes management practices in low-resource settings, since patients won’t have to go to hospital every day for their insulin injections,” said study author Philippa Boulle, a non-communicable diseases adviser at Doctors Without Borders.

Boulle said this would have to go hand-in-hand with patient education, support and follow-up so people with diabetes can measure their blood sugar levels and inject the proper amount of insulin.

The researchers hope for a consensus statement focusing on at-home use of insulin in high-temperature settings when no refrigeration is available. They also hope it will be endorsed by the World Health Organization .

People with type 1 diabetes inject insulin to help sugar enter cells. The disease causes elevated blood sugar levels, which can cause coma, blindness, amputation and death if not managed.

More information

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Does Novolog Insulin Need To Be Refrigerated When And Why The Guide

Its easy to get confused when storing medications. Given the different kinds of insulin available, it can make it confusing on whether or not each type can be refrigerated or has to be refrigerated after an amount of time.

With so many different insulins on the market, weve written this article to focus on whether or not needs to be refrigerated. First, heres a quick summary answer for you to take away, then well get into more detail.

Does Novolog need to be refrigerated? Its not compulsory for Novolog to be refrigerated until 28 days have passed. Using Novolog that is not refrigerated doesnt adversely affect a patient, but after 28 days, its recommended to refrigerate it to maintain the effectiveness. Bacterial growth can make Novolog less effective when it has not been refrigerated.

Now that weve seen the quick answer lets get into some more of the details about refrigerating Novolog.


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